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Breast cancer subtypes identified in genomic studies have different underlying genetic defects. Mutations in the tumor suppressor p53 occur more frequently in estrogen receptor (ER) negative, basal-like and HER2-amplified tumors than in luminal, ER positive tumors. Thus, because p53 mutation status is tightly linked to other characteristics of prognostic importance, it is

Title : Gene Expression Patterns Associated with p53 Status in Breast Cancer
Author : Applied Research Press
Language : en
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Type : PDF, ePub, Kindle
Uploaded : Apr 03, 2021

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